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Description

DNA methylation of HOXA10 in eutopic and ectopic endometrium

Crystal structure of the Rac1RhoGDI complex involved in nadph oxidase activation

A key mechanism is their function as histone deacetylase(HDAC) inhibitors, which epigenetically regulates gene expression in immune cells (Qu et al., 2023)

Recently, immunotherapy, including immune checkpoint inhibitors, has been applied clinically, and complete responses have been achieved in some ICC patients